Effects of Otago-based Multicomponent Exercise on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial

NCT06882720•Gdansk University of Physical Education and Sport

Summary

The objective of this clinical trial is to understand the efficacy of a targeted exercise program (Otago exercise program+Strength training) in elderly people with prefrailty and sarcopenia. The trial aims to answer the following main questions: * Is OEP+ST effective in elderly people with prefrailty and sarcopenia? * In what areas did participants improve during the OEP+ST intervention? Researchers will randomly assign participants to an experimental group (OEP+ST) and a control group (daily care only) for comparison to see the effects of this intervention. Participants in the EG group will: * Exercise 3 times a week for 1 hour each time (including 10 minutes of warm-up, 40 minutes of exercise and 10 minutes of stretching) At the same time, it is necessary to walk for 30-40 minutes three times a week. It lasts for three months. * Test and record their condition (including frailty, body composition, physical function, quality of life) before and after the experiment.

Eligibility

Age

65 - 89 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Participants were diagnosed with pre-existing frailty (Fried score 1-2); At the same time, they were also diagnosed with sarcopenia (according to AWGS Asian Sarcopenia Diagnostic Criteria 2019 edition: Grip strength: male \< 28kg, female \< 18kg; SMI: Male \< 7.0kg/m2, female \< 5.4kg/m2; Walking speed ≤1.0 m/s; 5 sit-up test times ≥12s); Simple mental status examination (MMSE score ≥21); There are no absolute contraindications to physical exercise (chest pain, chest tightness, palpitations, dyspnea, syncope, high fever, severe cough, severe diarrhea, gross hematuria, radiating pain in waist and legs, fracture, etc.).

Exclusion Criteria

•Uncontrolled high blood pressure. Coronary artery disease. Rheumatoid arthritis. Type 2 diabetes. Respiratory diseases and lung diseases. Are taking or have used antibiotics and/or antifungal therapy in the past 4 weeks.
•Unwillingness to stick to a prescribed schedule.

Locations (1)

Kunming Medical University

Kunming, Yunnan, China

Key Dates

Start Date

March 27, 2025

Primary Completion Date

June 27, 2025

Completion Date

June 28, 2025

Last Updated

July 3, 2025

Enrollment

ACTUAL participants

Conditions

Pre-FrailtySarcopenia in Elderly

Interventions

Exercise

BEHAVIORAL

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RECRUITING

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: July 3, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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Effects of Otago-based Multicomponent Exercise on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial

Inclusion Criteria

Exclusion Criteria

Evaluation of the JUICE HA® as an Anti-sarcopenia

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