Current Status of Islet Alpha Cell Function in Patients with Type 2 Diabetes

Exclusion Criteria

• •Patients who are allergic to GLP-1RA or have a BMI less than 24 kg/m\^2;
• •History of using blood sugar-lowering medications;
• •Estimated glomerular filtration rate (eGFR) less than 30 ml/(min\*1.73 m\^2);
• •History of drug abuse or alcohol dependence within the past 5 years;
• •Patients with poor compliance and irregular diet and exercise;
• •History of diagnosed pancreatitis, pancreatic tumor, medullary thyroid carcinoma, or diabetic retinopathy stage IV or higher;
• •Patients who have used systemic glucocorticoid therapy within the past 3 months;
• •Presence of infection or stress within the past four weeks;
• •Any other significant condition or comorbidity judged by the researcher, such as severe cardiopulmonary disease, endocrine disorders, neurological disorders, tumors, other pancreatic diseases, mental illness, history of alcohol or drug abuse.