Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells

Exclusion Criteria

• •Under 18 years of age
• •Prior surgery on affected knee
• •Diabetes
• •Root repair, inflammatory arthropathy, or any other concomitant procedure that cannot follow an accelerated PT protocol or any concomitant procedure that the PI deems exclusionary
• •Unable to attend physical therapy at Houston Methodist
• •Vulnerable populations
• •Immunocompromised patients such as those being treated for cancer, kidney failure, etc.
• •Heart disease (including systolic blood pressure \>180 mm Hg or heart failure)
• •Active infections
• •Non-English-speaking patients
• •Any known metal implants or allergy to contrast agents
• •Pregnancy (as part of standard of care, all female participants will be administered a urine pregnancy test prior to surgery. A negative result is required to proceed with surgery per SOC and thus, participate in the study) and those planning to become pregnant during the duration of the study
• •Any condition with known bleeding disorders, thrombus formation risk factors, or overlying wound and skin infections
• •Any condition in the opinion of the primary investigator that would compromise the integrity of the data collection or outcomes being assessed
• •Any other medical condition that in the opinion of the primary investigator would constitute a relative contraindication to study participation (e.g., Ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, SLE, scleroderma, polymyositis, Ehlers-Danlos syndrome, osteoporosis)