Lead Sponsor

Hospital Universitari de Bellvitge

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Age ≥18 years
•Patients hospitalised for the treatment of haematological malignancy or undergoing an autologous or allogeneic hematopoietic stem cell transplant or receiving CAR-T cell therapy
•Patients presenting with febrile neutropenia (defined as axillary temperature ≥ 38.0°C and \<500 neutrophils/mm3 or \<1000 with an expected rapid decrease in 24-48 hours),
•Patient to whom blood cultures are ordered as standard care for the microbiological diagnosis of the febrile neutropenia episode.

•Axillary temperature \<37.5ºC.
•High clinical suspicion of a non-infectious cause of fever at the moment when blood cultures are drawn (high suspicion of drug related fever, infusion reaction).
•Previously enrolled patients in whom the time between inclusion and the current episode is less than four weeks.
•Patients with febrile neutropenia in whom no blood cultures are drawn.