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Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria | Clinical Trials | Clareo Health

RECRUITING

Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria

Colonic Capsule Endoscopy for Screening of Neoplasms in Patients With Anaerobic Bacteremia

NCT06919068•Odense University Hospital

View on ClinicalTrials.gov

Summary

The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is: • How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Older than 18 years
•Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus.
•Able to provide oral and written informed consent
•Able to read and speak Danish

Exclusion Criteria

•Prior colorectal cancer diagnosis
•History of stenosis of the gastrointestinal tract
•Previous treatment of inflammatory bowel disease
•Previous major surgery of the gastrointesinal tract (e.g. gastric bypass)
•Colostomy
•Pacemaker/ICD
•Pregnancy or breastfeeding
•Allergies to the bowel preparation regimen
•Severe kidney disease
•Focus of infection in skin and soft tissue or outside the truncus (e.g. decubitus, diabetic foot ulcer)
+2 more criteria

Locations (1)

Odense University Hospital

Odense, Denmark

Key Dates

Start Date

April 23, 2025

Primary Completion Date

May 1, 2027

Completion Date

December 1, 2027

Last Updated

November 18, 2025

Enrollment

100

ESTIMATED participants

Conditions

Colorectal Cancer (CRC)Colorectal Cancer and Pre-cancer PolypsBlood Stream InfectionAnaerobic InfectionBacteriaemia

Interventions

Colon capsule endoscopy

DIAGNOSTIC_TEST

Contacts

Charlotte Nielsen Agergaard, MD

CONTACT

004565414797 charlotte.agergaard@rsyd.dk

Mark Bremholm Ellebæk, Professor

CONTACT

004540880511 Mark.Ellebaek1@rsyd.dk

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 18, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria

Inclusion Criteria

Exclusion Criteria

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