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A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent | Clinical Trials | Clareo Health

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A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent :A Controlled Clinical Trial

NCT06782087•Misr University for Science and Technology

View on ClinicalTrials.gov

Summary

The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile. The discoloration of teeth might be intrinsic, extrinsic, or combined. A variety of commercial bleaching agents is available. The most common substances used are carbamide peroxide or hydrogen peroxide or a mixture of sodium perborate and hydrogen peroxide.

Detailed Description

The aim of the study is to assess the effectiveness of two different in-office bleaching materials carbamide peroxide alone and carbamide peroxide with Chitosan nanoparticles Using diode laser as an activator Regarding tooth whitening and color stability 1 Day , 1 weeks, 1 month after treatment using Vita easy shade.

Eligibility

Age

18 - 40 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•discolored crown, non-vital or endodontically treated upper central and lateral incisors
•previous endodontic treatment performed two or more years earlier.

Exclusion Criteria

•caries on upper central and lateral incisors, inadequate fillings, and progressive periodontal disease.

Locations (1)

Misr University for science and technology

Giza, Egypt, Egypt

Key Dates

Start Date

October 15, 2025

Primary Completion Date

October 30, 2025

Completion Date

October 30, 2025

Last Updated

September 25, 2025

Enrollment

ESTIMATED participants

Conditions

Tooth Discoloration

Interventions

nano chitosan

DRUG

Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.

NCT06532526

Tooth Discoloration

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ACTIVE_NOT_RECRUITINGNA

Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials.

NCT06125132

Tooth DiscolorationTooth Wear

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 25, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

Inclusion Criteria

Exclusion Criteria

Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.

Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials.

Efficacy of Manual Toothbrushes in Removing Tooth Stains

Efficacy and Safety Assessment of Experimental Bleaching Agents

Combined Dental Bleaching Protocols and Time Required to Achieve Satisfactory Color

Patient Satisfaction of Glazed IPS Empress CAD Versus Glazed Celtra Duo Ceramic Laminate Veneers