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Efficacy of Manual Toothbrushes in Removing Tooth Stains | Clinical Trials | Clareo Health

COMPLETEDPHASE3

Efficacy of Manual Toothbrushes in Removing Tooth Stains

Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.

NCT06486974•Colgate Palmolive

View on ClinicalTrials.gov

Summary

Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.

Detailed Description

The aim of this study is to evaluate the effectiveness of manual toothbrushes in reducing tooth staining after 6 weeks of unsupervised, daily use by participants.

Eligibility

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Signed Informed Consent Form;
•Male and female subjects, aged 18-70, inclusive;
•Good general health and good oral health based on the opinion of the study investigator;
•Presence of permanent natural anterior teeth (no veneers/crowns/restorations that may interfere with this study scoring procedures);
•A minimum composite mean of 1.5 ≥ determined by the Lobene Tooth Stain Index;
•Available for the duration of the study;
•Clinical evidence of a tendency to form extrinsic stains on anterior teeth.

Exclusion Criteria

•Presence of orthodontic appliances/retainers involving scorable teeth;
•Presence of partial removable/fixed dentures and/or restorations involving scorable teeth;
•Tumor(s) of the soft or hard tissues of the oral cavity;
•Obvious signs of periodontal disease rampant caries, or any condition that the dental examiner considers exclusionary from the study;
•Five or more carious lesions requiring immediate care;
•Use of antibiotics, stain-inducing medications, and/or on any prescription that might interfere with the study outcome;
•Concurrent participation in another clinical study;
•Self-reported pregnancy and/or lactating women;
•Have used professional whitening product within one (1) year or had a dental prophylaxis (professional dental cleaning) within thirty (30) days - prior to the start of the study;
•History of allergies to oral care/personal care consumer products or their ingredients;
+1 more criteria

Locations (1)

Spa Dental

Santo Domingo, Dominican Republic

Key Dates

Start Date

September 23, 2024

Primary Completion Date

November 8, 2024

Completion Date

November 8, 2024

Last Updated

March 19, 2026

Enrollment

ACTUAL participants

Conditions

Tooth Discoloration

Interventions

NaF

DRUG

Na MFP

DRUG

Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.

NCT06532526

Tooth Discoloration

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ENROLLING_BY_INVITATIONPHASE1

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

NCT06782087

Tooth Discoloration

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ACTIVE_NOT_RECRUITINGNA

Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials.

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 19, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Efficacy of Manual Toothbrushes in Removing Tooth Stains

Inclusion Criteria

Exclusion Criteria

Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.

A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent

Evaluation of 2-year Clinical Performance of Two Different Single Color Universal Composite Resin Restorative Materials.

Efficacy and Safety Assessment of Experimental Bleaching Agents

Combined Dental Bleaching Protocols and Time Required to Achieve Satisfactory Color

Patient Satisfaction of Glazed IPS Empress CAD Versus Glazed Celtra Duo Ceramic Laminate Veneers