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Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest | Clinical Trials | Clareo Health

RECRUITINGNA

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest - A Randomized Clinical Trial

NCT06781892•Lars Wiuff Andersen

Summary

The "Strategies for Defibrillation during Out-of-Hospital Cardiac Arrest" (STRAT-DEFI) trial is an investigator-initiated, individually randomized, 3-group clinical trial comparing standard anterior-lateral pad positioning with anterior-posterior positioning and double sequential defibrillation during adult out-of-hospital cardiac arrest.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Out-of-hospital cardiac arrest
•2. Age ≥ 18 years
•3. ≥ 1 manual defibrillation attempt by emergency medical services
•4. Shockable rhythm as the last known rhythm
•5. Two manual defibrillators present on-site

Exclusion Criteria

•1. Blunt trauma, penetrating trauma, or burn injury suspected to be the cause of the cardiac arrest
•2. Prior enrollment in the trial
•3. Posterior pad placement not deemed possible by on-site clinician

Locations (6)

Emergency Medical Services, the North Denmark Region

Aalborg, Denmark

Danish Air Ambulance, Danish Regions

Aarhus N, Denmark

Prehospital Emergency Medical Services, Central Denmark Region

Aarhus N, Denmark

Copenhagen Emergency Medical Services, the Capital Region of Denmark

Ballerup Municipality, Denmark

The Prehospital Center, Region Zealand

Næstved, Denmark

Emergency Medical Services, the Region of Southern Denmark

Vejle, Denmark

Key Dates

Start Date

March 15, 2025

Primary Completion Date

March 1, 2028

Completion Date

March 1, 2029

Last Updated

May 23, 2025

Enrollment

909

ESTIMATED participants

Conditions

Cardiac Arrest (CA)

Interventions

Anterior-lateral pad positioning

OTHER

Anterior-posterior pad positioning

OTHER

Double-sequential defibrillation

OTHER

Contacts

Lars W Andersen

CONTACT

+4578414848 lwandersen@clin.au.dk

Bertram L Kirkegaard

CONTACT

bertramkirkegaard@clin.au.dk

Measurement of Airway Opening Index During Out-of-hospital Cardiac Arrest: The Lazarus AOI Trial.

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Cardiac Arrest (CA)Out-of-hospital Cardiac Arrest (OHCA)+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 23, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Strategies for Defibrillation During Out-of-Hospital Cardiac Arrest

Inclusion Criteria

Exclusion Criteria

Measurement of Airway Opening Index During Out-of-hospital Cardiac Arrest: The Lazarus AOI Trial.

Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training

The Application of Positive End-Expiratory Pressure in Out-of-Hospital Cardiac Arrest: The Lazarus-PEEP Trial.

Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

The Study Aims to Investigate the Frequency and Clinical Characteristics of Out-of-hospital Cardiac Arrests (OHCA) Occurring in Poland in 2023. This Research Seeks to Provide a Comprehensive Analysis of OHCA Incidents Across the Country, Focusing on Their Prevalence and the Associated Clinical fe

GARDE : GC7 (N1-guanyl-1,7 Diaminoheptane) cARDiac arrEst