Changshin Kang, MD. PhD

CONTACT

Lead Sponsor

Chungnam National University Hospital

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Patients receiving post-resuscitation care after out-of-hospital cardiac arrest for secondary brain injury treatment.
•Patients without contraindications for lumbar puncture catheter insertion for cerebrospinal fluid (CSF) collection. This includes the absence of:
•Uncontrolled diabetes.Coagulation disorders.
•Thrombocytopenia (platelet count $\< 100,000).
•A history of cirrhosis diagnosis.
•Current receipt of low molecular weight heparin.
•Current use of platelet inhibitors.
•A history of posterior spinal fusion that may interfere with catheter insertion.
•Local skin infection or rash at the puncture site.
•Signs of systemic infection or sepsis.
•A history of lumbar puncture within the past 6 hours.

•Cerebral Edema: Patients with evidence of cerebral edema on a brain computed tomography (CT) scan performed immediately after spontaneous circulation recovery.
•Patients who underwent extracorporeal membrane oxygenation (ECMO).
•Patients who could not maintain integrated therapy for more than 24 hours after cardiac arrest.
•Patients with a history of acute or chronic brain disease.

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