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Postprandial Responses to Fish Intake: in Vivo and in Vitro Study
Fish consumption has been increasing in recent decades due to consumer interest in the positive health effects of regular food intake, among other factors. Previous studies have described significant results on the acute consumption of fish products, favoring the reduction of triglycerides, total cholesterol, low-density lipoprotein, reduced insulin secretion, and increased plasma concentration of high-density lipoprotein during the postprandial period. Despite this scenario, studies investigating acute metabolic responses, such as postprandial physiological phenomena after consumption of the main fish species ingested by Brazilians, are still scarce. Thus, investigations of the acute effects of fish intake on postprandial metabolism may reveal new beneficial effects associated with this food group. The present proposal aims to compare the acute effects of the ingestion of two sources of fish and bovine protein on postprandial metabolism through the capillary blood sample collected within 5 hours after the ingestion of test meals, investigating hormones and inflammatory mediators and quantifying triglycerides, total cholesterol and non-esterified fatty acids and blood glucose, in addition to evaluating sensory aspects and satiety between different meals. It is expected to generate new data on postprandial physiology and investigate possible effects of fish ingestion that can contribute to public health management and healthy eating patterns.
Age
18 - 35 years
Sex
ALL
Healthy Volunteers
Yes
University of São Paulo
São Paulo, São Paulo, Brazil
Start Date
March 22, 2024
Primary Completion Date
September 1, 2025
Completion Date
December 1, 2025
Last Updated
January 3, 2025
30
ACTUAL participants
Assessment of postprandial metabolism after intake of different meat
OTHER
Lead Sponsor
University of Sao Paulo
Collaborators
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07229963