Study on the Treatment of Hepatitis B Virus(HBV) Infected Individuals With Peginterferon α-2b Combined With NA.

Exclusion Criteria

• •Allergy to interferon;
• •History of using telbivudine for antiviral treatment;
• •ALT(Alanine Aminotransferase) greater than 10 times the upper limit of normal, total bilirubin greater than 2 times the upper limit of normal;
• •Decompensated liver cirrhosis;
• •Neutrophil count \< 1.5 x 10\^9/L or platelet count \< 80 x 10\^9/L;
• •Presence of severe lesions in vital organs such as the cardiovascular, pulmonary, renal, brain, and fundus;
• •Those with autoimmune diseases, psychiatric disorders, poorly controlled diabetes, or thyroid dysfunction (hyperthyroidism or hypothyroidism);
• •Confirmed or suspected liver cancer or other malignant tumors;
• •Post-organ transplant or preparing for organ transplantation;
• •Currently using immunosuppressants;
• •Pregnant or planning to become pregnant within 2 years;
• •Alcohol or drug addicts;
• •HIV co-infection;
• •Other conditions deemed unsuitable for interferon use by the attending physician.