Remote Anxiety Management for ICS-resistant Asthma Study

Exclusion Criteria

• •1. Severe Psychiatric or Cognitive Disorders:
• •1. Diagnosis of major psychiatric disorders, such as major depressive disorder, bipolar disorder, schizophrenia, or other severe mental illnesses within the past six months, based on DSM-5 criteria.
• •2. Presence of cognitive impairments or neurological conditions, such as dementia or post-stroke complications, that may affect comprehension or adherence to the intervention.
• •3. Current psychiatric treatment involving antipsychotics, antidepressants, or sedatives that could interfere with the intervention's outcomes.
• •2. Substance Abuse or Dependence:
• •History of alcohol or drug abuse within the past six months, including but not limited to opioids, benzodiazepines, or illicit substances.
• •3. Severe Comorbidities:
• •1. Uncontrolled respiratory or cardiovascular conditions, such as chronic obstructive pulmonary disease (COPD), bronchiectasis, interstitial lung disease, heart failure, or uncontrolled hypertension, that could significantly impact asthma control and overall health.
• •2. Chronic diseases requiring long-term systemic corticosteroid therapy, such as rheumatic or autoimmune diseases, that may interfere with ICS treatment and study outcomes.
• •4. Pregnancy or Lactation:
• •Pregnant or breastfeeding women are excluded due to the unclear risks of ICS treatment and anxiety management interventions in these populations.
• •5. Allergic Bronchopulmonary Aspergillosis (ABPA) or Related Conditions:
• •Diagnosed ABPA or other respiratory diseases with mechanisms distinct from asthma, which could confound the assessment of ICS treatment effects.
• •6. Participation in Other Interventional Clinical Trials:
• •Participation in another interventional clinical trial within the past three months, particularly those involving respiratory diseases or medication adherence management, to avoid confounding effects on outcomes.
• •7. Incompatibility with Telephone-Based Interventions:
• •Inability to reliably receive or engage in telephone-based psychological interventions due to hearing impairments, communication barriers, or other reasons.
• •8. Adverse Reactions to Psychological Interventions:
• •Documented refusal of or adverse reactions to psychological interventions, such as phone-based relaxation or motivational interviewing, that could affect the feasibility and effectiveness of the study.
• •9. History of Major Surgery or Hospitalization:
• •History of major surgery or hospitalization (unrelated to asthma) within the past six months that might impact current health status and introduce bias into the study outcomes.