Remimazolam Besylate in Sedation of Postcardioperative Patients

Exclusion Criteria

• •1. pregnant or lactating women
• •2. known or suspected hypersensitivity to the study drug
• •3. history of impaired consciousness or psychiatric illness
• •4. severe bradycardia with a heart rate of \< 50 beats per minute
• •5. systolic blood pressure \< 90 mmHg with fluid resuscitation and vasopressor maintenance
• •6. atrioventricular block（II or III degree）, Left ventricular ejection fraction(LVEF) \<30%
• •7. participated in other clinical studies within 3 months