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Impact of Bevel Orientation on Arteriovenous Fistula Puncture in Hemodialysis: A Multicenter Randomized Comparative Study
End-stage renal disease (ESRD) is a condition in which the filtration function of the kidneys has deteriorated, necessitating dialysis or transplantation. With an aging population, the number of patients undergoing dialysis for CKD is constantly increasing. There are different types of dialysis treatment: hemodialysis and peritoneal dialysis. Hemodialysis involves exchanges between blood and a dialysate (a liquid used to purify blood) via a dialyzer (artificial filter), coordinated by a generator. This method requires a vascular approach, of which there are 3 types: the arteriovenous fistula (AVF), the arteriovenous graft and the central venous catheter. The AVF remains the vascular access of choice for hemodialysis sessions, and its preservation is an essential objective for patients with CKD. One of the major challenges for AVFs is to achieve a successful puncture, an act performed around 310 times a year per patient, for dialysis performed three times a week with double needles. This repeated procedure can cause damage to the AVF, leading to complications such as stenosis, thrombosis, aneurysm, superficial infection, hematoma, bleeding, parietal rupture or dissection. However, there is no official recommendation on the most conservative puncture technique for AVF. In view of the number of patients concerned and the recurrence of puncture, it would seem essential to evaluate the impact of bevel orientation on the occurrence of complications during dialysis by means of a randomized prospective study.
Age
18 - 85 years
Sex
ALL
Healthy Volunteers
No
Centre Hospitalier Emile Roux
Le Puy-en-Velay, France
Hôpital Saint Joseph Saint Luc
Lyon, France
Centre Hospitalier de Moulins-Yzeure
Moulins, France
Ctre Hospitalier Intercommunal Poissy St Germain Site Poissy
Poissy, France
Start Date
December 1, 2025
Primary Completion Date
June 30, 2028
Completion Date
June 30, 2029
Last Updated
July 31, 2025
240
ESTIMATED participants
Needle bevel orientation for arteriovenous fistula puncture
PROCEDURE
Lead Sponsor
Centre Hospitalier Emile Roux
Data Source & Attribution
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