A Study to Learn if the Study Medicine Called Itraconazole and if Food Changes How the Body Processes the Other Study Medicine Called PF 07258669 in Older Adults or Healthy Adults

Lead Sponsor

Pfizer

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

•1. Males and females who can no longer have children.
•2. Part A Only: At least 65 years old. Part B Only: At least 18 years old.
•3. In reasonably good health.
•4. Part A Only: Body mass index (BMI) of 16-27 kg/m2; and a total body weight \>40 kg (88 lb.). Part B Only: BMI of 16-32 kg/m2; and a total body weight \>50 kg (110 lb.).

•1. Evidence or history of clinically significant medical conditions.
•2. History of human immunodeficiency virus (HIV) infection, hepatitis B, or hepatitis C; positive testing for HIV, hepatitis B surface antigen (HBsAg), or hepatitis C antibody (HCVAb).
•3. History of alcohol abuse or binge drinking and/or any other illicit drug use or dependence within 6 months of Screening.
•4. Participation in studies of other investigational products (drug or vaccine) at any time during their participation in this study.

Related studies

NCT06631261 · Bronchiectasis Adult, Healthy Controls Group - Age and Sex-matched

NCT07258836 · Neoplasms, Healthy

NCT07545590 · Healthy

NCT00090662 · Healthy Volunteer

NCT07059858 · Intellectual Disability, Healthy Subjects