* Have a radiologically, cytologically, or histologically confirmed diagnosis of cancer
* Are treatment-naïve to a systemic cancer therapy, OR have a documented disease progression on standard-of-care treatment (for example, failure of chemotherapy, targeted therapy or immunotherapy)
* Have at least 1 imageable tumor that is 15 millimeter (mm) or larger in the longest diameter
Cohort 2
* Are overtly healthy at the Screening Visit and upon reporting to the clinic for the positron emission tomography (PET) Imaging Visit, as determined by medical evaluation including updated medical history, vital signs, physical examination, laboratory tests, and electrocardiogram (ECG)
You may not be if
Are pregnant or intend to become pregnant during their participation in the study
Are breastfeeding or intending to breastfeed during their participation in the study
Have a history of risk factors for Torsades de Pointes (for example, heart failure, hypokalemia, family history of Long QT Syndrome)
Are actively receiving cancer therapy or are in between cycles of treatment
Have a marked baseline prolongation of QT/corrected QT interval (QTc) interval (for example, repeated demonstration of a QTc interval greater than (\>) 450 millisecond (ms)
