Acute Effects of Paraxanthine on Energy and Focus

Exclusion Criteria

• •Current smoker or other nicotine use (i.e. vape, patch, etc.).
• •History of malignancy in the previous 5 years except for non-melanoma skin cancer (basal cell cancer or squamous cell cancer of the skin).
• •Prior gastrointestinal bypass surgery (Lapband, etc.).
• •Other known gastrointestinal or metabolic diseases that might impact nutrient absorption or metabolism, e.g. electrolyte abnormalities, diabetes, thyroid disease, adrenal disease, hypogonadism, short bowel syndrome, diarrheal illnesses, history of colon resection, gastric ulcer, reflux disease, gastroparesis, Inborn-Errors-of-Metabolism (such as PKU).
• •Chronic inflammatory condition or disease (e.g. rheumatoid arthritis, Crohn's disease, ulcerative colitis, Lupus, HIV/AIDS, etc.).
• •History of hepatorenal, musculoskeletal, autoimmune, or neurologic disease.
• •History of cognitive disorder.
• •History of psychiatric disorder.
• •Known sensitivity to any ingredient in the test formulations as listed in the Certificates-of-Analysis.
• •Women currently pregnant, trying to become pregnant or breastfeeding a child.
• •Use of anxiety or ADHD medication.
• •Caffeine intake of three or more cups of coffee or equivalent (\>400 mg) per day.
• •Alcohol consumption (more than 2 standard alcoholic drinks per day or more than 10 drinks per week) or drug abuse or dependence.
• •Clinically significant abnormal laboratory results at screening.
• •Prior gastrointestinal bypass surgery (Lapband, etc.).
• •Currently participating in another research study with an investigational product or have been in another research study in the past 30 days.
• •Any other diseases or conditions that, in the opinion of the medical staff, could confound the primary endpoint or place the subject at increased risk of harm if they were to participate.