The Effect of Intraperitoneal Instillation of Bupivacaine on Postoperative Pain After Surgical Laparoscopy

This randomized controlled trial will be conducted for (80) women undergoing laparoscopic procedures at endoscopy unit at El-Shatby Maternity University Hospital, after approval of ethical committee of Alexandria Faculty of Medicine. Randomization will be through opaque sealed envelopes. After signing their informed consents, the patients who are included in the study will be divided into two groups each group include (60) patients. Group A: Patients that will receive intraoperative instillation of bupivacaine. Group B: (Control group) that will not receive the medication. The patients in both groups will be subjected to: Pre-operative: History taking (gynecological, obstetric, medical any drug reaction and surgical), general examination and abdominal examination. Intra-operative: premedication : 1.5 microgram/kg fentanyl IV induction of anathesia: 2mg/kg Propofol IV , 0.5 mg/kg Atracurium IV , ventilation via face mask 2-3 minutes , then endotracheal intubation 1gm paracetamol IV as intraoperative analgesia which will not interfere with postoperative pain scoring. Group (A) only will receive intra-peritoneal 40 ml bupivacaine 0.2%, after laparoscopic procedure before removing trocars.