Loading clinical trials...

Evaluation of an Anti-TREM-1 Treatment on an ex Vivo Human Intestinal Model | Clinical Trials | Clareo Health

RECRUITING

Evaluation of an Anti-TREM-1 Treatment on an ex Vivo Human Intestinal Model

NCT06580418•Inotrem

Summary

TIME is an observational study performed on UC and CD patients under endoscopic surveillance for monitoring the clinical activity of their disease. The main objective of the study is to confirm the therapeutic potential of TREM-1 in inflammatory bowel disease.

Eligibility

Age

18 - 60 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Patients between 18 and 60 years
•Signed informed consent
•Ulcerative colitis (UC) patients with active disease
•Crohn's disease (CD) patients with active disease

Exclusion Criteria

•UC or CD patients in remission
•Patients between 18 and 60 years without informed consent

Locations (1)

IRCCS San Raffaele

Milan, Italy

Key Dates

Start Date

January 31, 2023

Primary Completion Date

March 31, 2025

Completion Date

March 31, 2025

Last Updated

February 27, 2025

Enrollment

ESTIMATED participants

Conditions

Inflammatory Bowel Diseases

Interventions

Additional biopsies and blood samples

OTHER

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883

Inflammatory Bowel DiseasesCrohn's Disease

View study

RECRUITING

Institutional Registry of Rare Diseases

NCT06573723

Rare DiseasesAmyloidosis+24 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 27, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

Evaluation of an Anti-TREM-1 Treatment on an ex Vivo Human Intestinal Model

Inclusion Criteria

Exclusion Criteria

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Institutional Registry of Rare Diseases

Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Clinnova-IBD, a Prospective Cohort of Patients With Inflammatory Bowel Disease (IBD)

Therapeutic Endpoint in Pediatric IBD Conditions