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MUDgame A Randomized Multi-Arm Controlled Experiment for Measuring the Benefits of an Exergame-based Intervention on Neuro-cognitive Functions in Adults Suffering From Depression
The purpose of this study is to analyse the changes derived from exergames (videogames that include cognitive and physical stimulation simultaneously), in terms of cognitive functioning, psychomotor abilities, and its neural substrate, in adults suffering from depression.
The experiment will consist in a randomized three-arms controlled study. After being informed about the study and potential risks, and given written informed consent, adult participants with depression will be randomly distributed into three experimental groups: an intervention group that will train with exergames, an active control group that will train only with cognitive games, and a passive control group or wait-list. Cognitive Functions will be evaluated in three different moments: before the training intervention, after the intervention, and three months after finishing the training intervention. Researchers will collect cognitive-behavioral and neural information (event-related potentials), and performing analysis of variance to compare the outcomes of the diverse groups at the three different time points, scientists will analyse the benefits of exergames on cognition.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Start Date
January 1, 2027
Primary Completion Date
February 1, 2028
Completion Date
March 1, 2029
Last Updated
July 17, 2025
150
ESTIMATED participants
Exergame-Based Training
BEHAVIORAL
Cognitive-Based Training
BEHAVIORAL
Wait-List
BEHAVIORAL
Lead Sponsor
MAP Institute
NCT07360600
NCT06793397
Data Source & Attribution
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