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Sleep Restriction and Parental History of Hypertension | Clinical Trials | Clareo Health

RECRUITINGNA

Sleep Restriction and Parental History of Hypertension

NCT06482814•Mayo Clinic

Summary

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.

Eligibility

Age

18 - 35 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Healthy adults aged 18-35 years
•Absence of any significant medical or psychiatric disease (as per the investigators' judgment)
•Nonsmoker
•Nonpregnant
•History of normal sleep duration (reported average sleep duration between 7-9 hours/night and no habitual napping)
•Hypertension status information available for both biological parents
•Ability to understand study procedures and to comply with them for the entire length of the study
•Ability to understand English and provide informed consent

Exclusion Criteria

•Age \<18 or \>35 years
•Body mass index \<18.5 or ≥30 kg/m2
•Pregnant or lactating
•Unable to determine history of HTN in participant's biological parents or subject being adopted
•Use of tobacco, vaping, marijuana products or other drugs
•Excessive caffeine consumption (\>400 mg/day)
•Excessive alcohol consumption (\>7 drinks/week for women, \>14 drinks/week for men)
•Office SBP/DBP ≥130/80 mmHg
•Daytime ambulatory SBP/DBP ≥130/80 mmHg
•Fasting glucose ≥126 mg/dl
+14 more criteria

Locations (1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

Key Dates

Start Date

February 20, 2025

Primary Completion Date

April 1, 2029

Completion Date

April 1, 2029

Last Updated

August 1, 2025

Enrollment

ESTIMATED participants

Conditions

Hypertension

Interventions

Partial sleep deprivation (sleep restriction)

BEHAVIORAL

Normal sleep

BEHAVIORAL

Contacts

Sabah Munir

CONTACT

(507)255-0151 Munir.Sabah@mayo.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 1, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Sleep Restriction and Parental History of Hypertension

Inclusion Criteria

Exclusion Criteria

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