BOne Metastases REgistry for Patients Undergoing cryoAbLation With curatIve purpoSe

Exclusion Criteria

• •\< 18 years old;
• •Incapacity or refusal to give informed consent;
• •Ongoing pregnancy;
• •Health status not compatible with the minimum meaningful follow-up period (i.e., 12 months):
• •* Karnofsky Performance Scale \< 60%, or
• •* Bone metastases originating from rapidly evolving tumour histologies not allowing reasonable life expectancy of at least 12 months, or
• •* Life expectancy \< 12 months
• •Infection of treatment site or systemic infection;
• •Uncorrectable coagulopathy;
• •Haematological disease (including multiple myeloma and plasmacytoma);
• •Concomitant radiation therapy or radiation therapy within 12 weeks before the planned cryoablation procedure.