Liqun Zhang

CONTACT

Lead Sponsor

Adai Technology (Beijing) Co., Ltd.

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

•1. Meets the diagnostic criteria for depression according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition), without psychotic symptoms, as recurrent outpatient or inpatient.
•2. Patients with a Montgomery-Asberg Depression Rating Scale (MADRS) score ≥ 22 before randomization.
•3. Age ≥ 18 and ≤ 65 years, regardless of gender.
•4. Understands the trial and signs the informed consent form.

•1. Meets criteria for other psychiatric disorders according to the DSM-5, including schizophrenia spectrum disorders, bipolar and related disorders, neurodevelopmental disorders, neurocognitive disorders, or depression due to substance and/or medication or other medical conditions.
•2. History of substance and/or alcohol abuse within the past year.
•3. Significant risk of suicide (MADRS item 10 score = 4).
•4. Difficulty or inability to communicate verbally, understand or follow instructions, or cooperate with treatment and assessment.
•5. Inability to use a smartphone.
•6. Deemed unsuitable for participation by the researcher.