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Evaluation of Thyroid Function and Autoimmunity in Subfertility Women and Thyroid Hormone Levels in the First Trimester of Assisted Reproduction
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of low-grade inflammation. There are no studies about the detection of these autoantibodies in infertile women. Our objective is to evaluate the association between ovarian reserve and thyroid function and its autoimmunity in infertile women seeking for assisted reproductive treatment (ART).Evaluation ot thyroid function in the first trimester in also be evaluated in women submitted to ART.
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of low-grade inflammation. There are no studies about the detection of these autoantibodies in infertile women. Evaluation of TSH profile during ovarian stimulation in ART is also debated in literature with conflicting results. Our objective is to evaluate the association between ovarian reserve and thyroid function and its autoimmunity in infertile women seeking for assisted reproductive treatment (ART) and TSH profile during ovarian stimulation and during the first trimester.
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
Yes
Vida Assisted Reproduction clinic - Fertility Center
Rio de Janeiro, Rio de Janeiro, Brazil
Start Date
July 1, 2021
Primary Completion Date
July 31, 2023
Completion Date
July 31, 2023
Last Updated
May 1, 2024
453
ACTUAL participants
Non Applicable
OTHER
Lead Sponsor
Rio de Janeiro State University
NCT04785443
NCT06112340
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View ClinicalTrials.gov Terms and ConditionsNCT04390308