Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol

Xiang Li

CONTACT

Lead Sponsor

Beijing Friendship Hospital

Age

50 - 80 years

Sex

ALL

Healthy Volunteers

No

•Age range: 50-80 years
•Diagnosis of LSS affecting 1-2 vertebral levels
•Predominant manifestation of neurogenic intermittent claudication, with ineffective conservative treatment for at least 3 months
•Presence of lumbar DS of less than grade II and absence of spine instability
•Willingness to participate in the study and complete follow-up assessments.

•Diagnosis of isthmic lumbar spondylolisthesis or lumbar DS of grade ≥II
•Evidence of instability at the affected vertebral level (intervertebral angle change \> 15° and/or vertebral translation ≥ 4.5 mm in standing flexion-extension radiographs of the lumbar spine)
•History of prior surgery at the affected vertebral level
•Presence of scoliosis with a Cobb angle \>20º
•Presence of other conditions affecting the lumbar spine (infection, tumor, fracture, neurological diseases, and others)
•Medical disorders that preclude surgical tolerance
•Participation in other clinical research projects related to the treatment of lumbar spinal stenosis.