A Study of LC542019 in Healthy Subjects and Subjects With T2DM

Exclusion Criteria

• •History of or current diagnosis of Diabetes Mellitus Type 1 or Diabetes Mellitus Type 2
• •History of or current significant diagnosis of cardiovascular, respiratory, hepatic, renal, gastrointestinal endocrine, hematological, or neurological disorders or abnormalities, or other major systemic disease
• •History of or presence of clinically significant ECG findings
• •History of or acute significant gastrointestinal disorder
• •For T2DM subjects:
• •History of or current diagnosis of Diabetes Mellitus Type 1
• •A subject who has acute proliferative retinopathy or maculopathy, severe gastroparesis, and/or severe neuropathy, especially autonomic neuropathy
• •Recurrent major hypoglycemia or hypoglycemic unawareness or recent ketoacidosis
• •Current use of any prescribed or non-prescribed drugs (other than current treatment for diabetes mellitus or birth control methods)