To Evaluate the Clinical Study of CUD005 Injection in Patients With Cirrhosis

Exclusion Criteria

• •1. Subjects who were Allergic to cell therapy, steroids, and related drugs used in the study；
• •2. Have malignant tumors, history of organ transplantation or tissue regeneration therapy, active, known or suspected autoimmune diseases, idiopathic pulmonary fibrosis, interstitial pneumonia, pneumoconiosis, radiation pneumonia, drug-induced pneumonia, active pneumonia, heart disease that is not well controlled, hypertension, etc;
• •3. Subjects with stage III or IV hepatic encephalopathy within 3 months before apheresis or currently diagnosed；
• •4. Virology shows anti-HCV antibodies, HIV-positive, or syphilis antibodies during the screening period；
• •5. Subjects were HBV surface antigen positive and HBV-DNA titer was ≥ 20 IU/mL during the screening period；
• •6. Subjects with clinically symptomatic ascites or pleural effusions requiring puncture drainage. Or who had received thoracic and ascites drainage within 2 weeks prior to treatment, had may only show a small amount of ascites or pleural effusions on imaging, except in those without clinical symptoms；
• •7. According to the judgment of the investigator, the subjects had other factors that may cause the study to be terminated halfway, such as other serious concomitant diseases (such as severe diabetes, mental illness, drug use, etc.), serious laboratory abnormalities, accompanied by family or social factors, which will affect the safety of the subject, or the collection of data and samples.