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RECRUITINGNCT07343037

Diagnosis of Lymphohistiocytic Hemophagocytosis in Intensive Care

Patients with hepatocellular insufficiency and/or cirrhosis are at risk of developing invasive fungal infections, particularly in critical care settings. In international recommendations, voriconazol...

Lead sponsor: University Hospital, Strasbourg, France•1 locations•View source on ClinicalTrials.gov

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Contacts

Antonin HUGEROT, MD

CONTACT

33 3 88 12 79 24 antonin.hugerot@chru-strasbourg.fr

Sponsors

Lead Sponsor

University Hospital, Strasbourg, France

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Adult patient (≥18 years old)
•Patient admitted to the intensive care unit at Hautepierre Hospital, Strasbourg University Hospital, between January 1, 2014, and December 31, 2024
•At least 3 biological signs of HLH:
•* ferritin \> 2000 ng/mL
•* triglycerides \> 1.5 g/L
•* at least one cytopenia (leukocytes ≤ 5000 G/L, platelets ≤ 110 G/L, hemoglobin ≤ 9.2 g/dL).

Exclusion Criteria

•Refusal to participate in the study

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 15, 2026Terms

Trial snapshot

StatusRECRUITING

Phase—

Enrollment100

Start dateAug 2025

Last updatedJan 15, 2026

Condition

Hepatic Insufficiency Cirrhosis, Liver

Locations shown

Médecine intensive - Réanimation - CHU de Strasbourg - France

Strasbourg

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 15, 2026Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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