A Trial of Hydrus Microstent Versus Goniotomy

Exclusion Criteria

• •Prior argon laser trabeculoplasty, laser peripheral iridotomy, incisional glaucoma surgery, or cyclophotocoagulation
• •Selective laser trabeculoplasty within 90 days of study enrollment
• •Iridotrabecular contact for 180 degrees or greater
• •Peripheral anterior synechiae in nasal or inferior angle
• •Best corrected visual acuity worse than 20/200
• •Phacodonesis on pre-operative examination
• •Vitreous in anterior chamber on pre-operative examination
• •Nanophthalmos
• •Anti-platelet and anticoagulant medications other than aspirin 81mg daily
• •Active treatment for another ophthalmic condition in either eye (e.g., anti-VEGF injections, steroids for corneal transplant)
• •Abnormality in study eye that could affect tonometry
• •Glaucoma diagnosis other than the above
• •Normal tension glaucoma
• •Conditions that can cause elevated episcleral venous pressure (e.g., Sturge-Weber syndrome, Graves disease, retrobulbar tumor)
• •History of uveitis in either eye
• •Inability to complete gonioscopy examination
• •Use of oral steroids within 90 days or anticipated use of oral steroids
• •Oral medications that can affect IOP, including oral carbonic anhydrase inhibitors such as acetazolamide and methazolamide
• •History of steroid-associated IOP elevation
• •Medically unfit for attending planned study visits
• •Involvement in another interventional research study