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Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications | Clinical Trials | Clareo Health

RECRUITING

Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

NCT04354545•University of California, Los Angeles

View on ClinicalTrials.gov

Summary

To evaluate glaucoma patients' response to treatment with Xiidra, an FDA-approved drug for ocular surface discomfort, which will be prescribed as standard of care treatment.

Detailed Description

To assess glaucoma patients' response to treatment with Xiidra (Lifitegrast ophthalmic solution) 5% for ocular surface discomfort caused, in part, by topical glaucoma antihypertensive medications.

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Currently using one or more topical glaucoma antihypertensives
•Self-described symptoms of ocular surface discomfort
•Xiidra is being prescribed as part of the subject's standard care

Exclusion Criteria

•History of glaucoma filtration surgery, history of ocular surface surgery (pterygium, conjunctivoplasty, etc.),
•current use of topical cyclosporine
•current use of topical steroids
•incisional ocular surgery within 6 months

Locations (1)

Doheny Eye Center UCLA

Fountain Valley, California, United States

Key Dates

Start Date

April 1, 2021

Primary Completion Date

December 1, 2026

Completion Date

December 1, 2026

Last Updated

March 13, 2026

Enrollment

ESTIMATED participants

Conditions

GlaucomaOcular Surface Disease

Interventions

Xiidra (Lifitegrast ophthalmic solution) 5%

DRUG

Contacts

Benjamin B Bert, MD

CONTACT

626-817-4701 BBert@mednet.ucla.edu

Mayra Raygoza

CONTACT

16268174747 Mraygoza@mednet.ucla.edu

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Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 13, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

Inclusion Criteria

Exclusion Criteria

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