Lead Sponsor

Centre Hospitalier Annecy Genevois

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Adults
•Patients informed and did not object to the collection of their medical data for the study
•Patient admitted in Trauma center between January 2016 and December 2018 severe head injury defined by a Glasgow Coma Scale (GCS) \< 9 AND/OR Abnormalities on the first brain CT-scan with pathological transcranial Doppler (Vd \< 25 cm/s and IP \> 1.25)

•Abbreviated Injury Score (AIS) head and neck ≤ 3 AND/OR AIS out of head and neck \> 3
•Taking drugs that interfere with hemostasis, such as anticoagulant or antiplatelet antiaggregants in preventive or curative doses;
•Patients under guardianship
•Patients still alive at the time of data collection AND opposed to the collection of their data