Adult patients, male or female, suffering from spasticity of neurological origin (multiple sclerosis, stroke, head trauma, etc.) and eligible for botulinum toxin injection treatments.
Patients with known pain and/or anxiety
Able to give informed consent to participate in research
Enrolled in a French Social Security system
You may not be if
Contraindication to musical intervention (severe hearing impairment, unstabilized psychotic disorders, history of auditory trauma)
Major cognitive impairment
Any medical condition deemed by the investigator to be incompatible with the research.
Indication for MEOPA sedation during botulinum toxin injection sessions
Medication or medical conditions likely to interfere with heart rate variability during the study: beta-blockers, anti-arrhythmics, anxiolytics, benzodiazepines, anti-hypertensives and calcium antagonists.