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Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for hip arthroplasty
This study is proposed to explore the effect of perineurial Dexamethasone and Dexmedetomidine on erector spinal plane block duration for spine surgery. After spine surgery, patients need good analgesia. Peripheral nerve blocks have provided a safe, effective method to control early postoperative pain when symptoms are most severe. The safety of local anaesthesia is essential due to the much lower toxicity threshold of local anaesthetics. An effective adjuvant, such as Dexamethasone or Dexmedetomidine, could allow for a higher dilution of local anaesthetics while maintaining and enhancing their analgesic effect. There is considerable research where intravenous and perineural dexamethasone and Dexmedetomidine use have been compared in adults. However, there is a massive lack of research regarding spine surgery and the Erector Spinae Plane Block. In this study, investigators compare perineural Dexamethasone and Dexmedetomidine. The investigator aims to find a dexamethasone or dexmedetomidine that covers the need for good pain relief and fast recovery postoperatively.
Age
18 - 100 years
Sex
ALL
Healthy Volunteers
No
Poznan University of Medical Sciences
Poznan, Poznań, Poland
Start Date
April 10, 2024
Primary Completion Date
March 30, 2025
Completion Date
May 30, 2025
Last Updated
April 29, 2024
30
ESTIMATED participants
0.9%sodium chloride
DRUG
Dexamethasone
DRUG
Dexmedetomidine
DRUG
Lead Sponsor
Poznan University of Medical Sciences
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT07288983