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Brain Network Analysis of Anesthesia Characteristics in Patients With Prolonged Disorders of Consciousness Based on Polysomnography
The goal of this prospective, exploratory and observational study is to learn about in healthy volunteers and patients with prolonged disorders of consciousness(pDoC). The main questions it aims to answer are: 1. Observe the similarities and differences of polysomnography between pDoC patients and healthy volunteers, and analyze the characteristic brain network changes based on polysomnography 2. To observe the similarities and differences of polysomnography in pDoC patients before and after Insertion of spinal cord electric stimulator under general anesthesia,and analyze the changes of anesthesia characteristic brain network in patients with consciousness disorders based on polysomnography. 3. To observe the similarities and differences of polysomnography in pDoC patients before and after spinal cord stimulation,and analyze the characteristic changes of brain network after spinal cord stimulation. We will record the 8h polysomnography of healthy volunteers,record the polysomnography of DOC patients before and 24 hours after operation;and record the 24h polysomnography of patients with spinal cord electric stimulator.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
Yes
Beijing Tiantan Hospital
Beijing, China
Start Date
January 11, 2023
Primary Completion Date
June 1, 2025
Completion Date
June 1, 2025
Last Updated
August 1, 2024
60
ESTIMATED participants
General Anesthetics
DRUG
Lead Sponsor
Beijing Tiantan Hospital
NCT06323031
NCT06426602
NCT06464549
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