Driving Pressure During General Anesthesia for Minimally Invasive Abdominal Surgery (GENERATOR)

Exclusion Criteria

• •1. planned for open abdominal surgery;
• •2. planned for surgery in lateral or prone position;
• •3. planned for combined abdominal and intra-thoracic surgery
• •4. confirmed pregnancy;
• •5. consent for another interventional trial during anesthesia;
• •6. having received invasive ventilation \> 30 minutes within the last five days;
• •7. any previous lung surgery;
• •8. history of previous severe chronic obstructive pulmonary disease (COPD) with (noninvasive) ventilation or oxygen therapy at home or repeated systemic corticosteroid therapy for acute exacerbations of COPD;
• •9. history of acute respiratory distress syndrome (ARDS);
• •10. expected to require postoperative ventilation;
• •11. expected hemodynamic instability or intractable shock;
• •12. severe cardiac disease (New York Heart Association class III or IV, acute coronary syndrome or persistent ventricular tachyarrhythmia's).