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Effects of Antimicrobial Photodynamic Therapy in Non-surgical Periodontal Treatment of Patients with Obesity
The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
Bauru School of Dentistry
Bauru, São Paulo, Brazil
Start Date
October 9, 2023
Primary Completion Date
April 30, 2025
Completion Date
June 30, 2025
Last Updated
December 5, 2024
24
ESTIMATED participants
antimicrobial photodynamic therapy (aPDT)
PROCEDURE
Control
PROCEDURE
Lead Sponsor
University of Sao Paulo
NCT07472881
NCT01143454
Data Source & Attribution
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