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Innate Immunity in Allergic Asthma | Clinical Trials | Clareo Health

RECRUITING

Innate Immunity in Allergic Asthma

NCT06068335•University of Central Florida

Summary

The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Participants must be at least 18 years of age
•no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion Criteria

•Pregnant women and prisoners will be excluded from the study.
•Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded.

Locations (1)

University of Central Florida

Orlando, Florida, United States

Key Dates

Start Date

October 18, 2021

Primary Completion Date

June 1, 2025

Completion Date

June 1, 2025

Last Updated

December 6, 2024

Enrollment

100

ESTIMATED participants

Conditions

Asthma

Contacts

Amoy Fraser, PhD, CCRP, PMP

CONTACT

4072668742 amoy.fraser@ucf.edu

Erica Martin, B.S.

CONTACT

4072668742 erica.martin@ucf.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 6, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Innate Immunity in Allergic Asthma

Inclusion Criteria

Exclusion Criteria

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

Blood Eosinophil Guided Versus Usual Care In The Management Of Mild To Moderate Asthma at Primary Care (BEAM)

Relationship of Airway Microbiota, Endotype and Phenotype in Adult Asthma

To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

A Study to Investigate Efficacy and Safety of PT027 Compared With PT007 in Symptomatic Chinese Adults With Asthma