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An Exercise Intervention to Improve Overall Brain Health | Clinical Trials | Clareo Health

COMPLETEDNA

An Exercise Intervention to Improve Overall Brain Health

An Exercise Intervention to Improve Overall Brain Health: PEDAL (Physical Education for an Active Lifestyle) Study

NCT06035094•University of Alabama at Birmingham

Summary

The goal of this clinical trial is to test the effects of 10 weeks of exercise on overall brain health, reduction in blood pressure, and the number of blood vessels in the back of the eyes in patients with hypertension and have a body mass index ≥ 25 kg/m2. The main question\[s\] it aims to answer are: * To test the effect of moderate vs intensive exercise on Brain Care Score outcomes. * To ascertain the differential impact of moderate vs high intensity exercise in reducing hypertension and its downstream effects.

Eligibility

Age

35 - 65 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•diagnosed with hypertension
•have a body mass index ≥ 25 kg/m2
•are between the ages of 35-65 years old
•access to a smart phone that allows installation of 2 two applications that record your workouts
•pass a fitness evaluation.

Exclusion Criteria

•do not have hypertension
•weight over 300 lbs
•unable to pass the fitness evaluation
•BMI less than 25kg/m2

Locations (1)

UAB

Birmingham, Alabama, United States

Key Dates

Start Date

January 23, 2024

Primary Completion Date

January 12, 2026

Completion Date

January 12, 2026

Last Updated

January 14, 2026

Enrollment

ACTUAL participants

Conditions

Brain Care ScoreExerciseHypertensionBMI

Interventions

Exercise Intervention to improve overall Brain Health

BEHAVIORAL

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RECRUITINGNA

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 14, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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An Exercise Intervention to Improve Overall Brain Health

Inclusion Criteria

Exclusion Criteria

Natural History of Noncirrhotic Portal Hypertension

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