Effectiveness and Safety of Probiotic in Regulating Chronic Constipation

Exclusion Criteria

• •1. Diabetic patients.
• •2. Pregnant patients.
• •3. Breastfeeding patients.
• •4. Patients requiring antibiotic treatment.
• •5. Patients requiring treatment with tricyclic antidepressants, antiepileptics, antihistamines, antiparkinsonians, antipsychotics, antispasmodics, verapamil, monoamine oxidase inhibitors, opiates, sympathomimetics, antacids (with aluminum and calcium), antidiarrheals and nonsteroidal anti-inflammatory drugs.
• •6. Patients who change the type of diet during the study.
• •7. Patients with allergy or intolerance to any of the ingredients in the formulation of the product under study.
• •8. Subjects with a history of pharmacological, alcoholic, or other substance abuse, or other factors that limit their ability to cooperate during the study.
• •9. Excessive alcohol consumption (\>3 glasses of wine or beer/day).
• •10. Subjects whose condition does not make them eligible for the study, according to the researcher.