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In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical stimulation (WPHF NMES) in various populations. The investigators will use WPHF NMES contractions as a model to gain insights into the mechanisms underlying muscle cramps, restless legs syndrome or stroke-induced spasticity as there is evidence that they share common underlying mechanisms. The investigators will then use WPHF NMES as a training modality to improve plantar flexor neuromuscular function in stroke patients by taking advantage of their motoneuronal hyperexcitability.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Bâtiment Synathlon, quartier UNIL-Centre
Lausanne, Switzerland
Start Date
October 1, 2023
Primary Completion Date
December 31, 2025
Completion Date
December 31, 2026
Last Updated
November 28, 2023
110
ESTIMATED participants
wide pulse high frequency neuromuscular electrical stimulation training
OTHER
Lead Sponsor
University of Lausanne
Collaborators
NCT05093673
NCT07371455
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT06258538