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ERCP Plus Laparoscopic Cholecystectomy Versus Laparoscopic Common Bile Duct Exploration and Cholecystectomy | Clinical Trials | Clareo Health

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ERCP Plus Laparoscopic Cholecystectomy Versus Laparoscopic Common Bile Duct Exploration and Cholecystectomy

ERCP Plus Laparoscopic Cholecystectomy Versus Laparoscopic Common Bile Duct Exploration and Cholecystectomy for Cholecystocholedocholithiasis - The Same Operator: A Multicenter Randomized Controlled Trial

NCT05901363•South Valley University

View on ClinicalTrials.gov

Summary

Detailed Description

Around 10-18% of patients undergoing cholecystectomy for gallstones have common bile duct (CBD) stones. Currently, various procedures for the treatment of cholecystocholedocholithiasis are available including open cholecystectomy plus open common bile duct exploration (OC+OCBDE), laparoscopic cholecystectomy plus laparoscopic common bile duct exploration (LC+LCBDE), may be trans-cystic or trans-choledochal, and laparoscopic cholecystectomy plus endoscopic retrograde cholangiopancreatography (LC+ERCP), which may be performed pre, at, or after LC. Single-session treatment of gallbladder and CBD stones is safe, efficient, shortens hospital stay, and is less expensive than staged procedures. Although there is some evidence suggesting that LCBDE may be associated with a lower rate of retained stones compared with ERCP, previous studies comparing LCBDE with ERCP and stone extraction have collectively failed to demonstrate the superiority of one approach over the other.

Eligibility

Age

20 - 70 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•1. Patients diagnosed with cholecystocholedocholithiasis
•2. American Society of Anesthesiologists (ASA) scores of I-III
•3. Age 20-70 years.

Exclusion Criteria

•1. cholangitis,
•2. acute biliary pancreatitis,
•3. suspected Mirizzi syndrome,
•4. suspected hepatobiliary malignancy,
•5. perforated gallbladder,
•6. biliary peritonitis,
•7. intrahepatic stones,
•8. pregnancy,
•9. previous cholecystectomy,
•10. altered anatomy such as Billroth II reconstruction or any form of Roux-en-Y reconstruction that interfere with the endoscopic approach,
+1 more criteria

Locations (1)

Mohammed Ahmed Omar

Qina, Qena Governorate, Egypt

Key Dates

Start Date

February 1, 2019

Primary Completion Date

October 30, 2021

Completion Date

October 30, 2022

Last Updated

June 13, 2023

Enrollment

218

ACTUAL participants

Conditions

Common Bile Duct Calculi

Interventions

Endoscopic retrograde cholangiopancreatography plus laparoscopic cholecystectomy

PROCEDURE

aparoscopic common bile duct exploration and laparoscopic cholecystectomy

PROCEDURE

Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube Drainage

NCT07345663

Common Bile Duct Calculi

View study

COMPLETED

ERCP and LC for Cholecystocholedocholithiasis in Children: Should It Be Accomplished in One or Repeated Hospitalization?

NCT06672991

CholedocholithiasisCholecystolithiasis+4 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 13, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

ERCP Plus Laparoscopic Cholecystectomy Versus Laparoscopic Common Bile Duct Exploration and Cholecystectomy

Inclusion Criteria

Exclusion Criteria

Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube Drainage

ERCP and LC for Cholecystocholedocholithiasis in Children: Should It Be Accomplished in One or Repeated Hospitalization?

Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

SpyGlass Versus ESWL for Large Common Bile Duct Stones

Short Duration Versus Fourteen Days Antibiotic in Common Bile Duct Cholangitis

Endoscopic Nasogallbladder Drainage Versus Gallbladder Stenting Before Cholecystecomy