The Effects of the GOLO for Life® Plan and Release Supplement on Weight Management in Overweight and Obese Adults

Exclusion Criteria

• •1. Individuals who are pregnant, breast feeding, or planning to become pregnant during the study
• •2. Allergy, sensitivity, or intolerance to the investigational product ingredients
• •3. Gastric bypass surgery or other surgeries to induce weight loss
• •4. Metal implants or other physical characteristics/limitations that may affect DEXA scan results, as assessed by the QI
• •5. Current participation within the last three months in any weight loss or diet programs
• •6. Current or history of eating disorders, as assessed by the QI
• •7. Obesity-induced by metabolic or endocrinologic disorders (ex. acromegaly, hypothalamic obesity), as assessed by the QI
• •8. Current or history of significant diseases of the gastrointestinal tract, as assessed by the QI
• •9. Chronic inflammatory diseases, as assessed by the QI
• •10. Type I diabetes
• •11. Type 2 diabetes if on insulin treatment
• •12. History of gout and have had a flare up within 12 months, as assessed by the QI
• •13. Current unstable diagnosis with kidney and/or liver diseases as assessed by the QI on a case-by-case basis, with the exception of history of kidney stones in participants who are symptom free for 6 months
• •14. Self-reported confirmation of current or pre-existing thyroid condition. Treatment on a stable dose of medication for at least 3 months will be considered by the QI
• •15. Major surgery in the past 3 months or individuals who have planned surgery during the course of the study. Participants with minor surgery will be considered on a case-by-case basis by the QI
• •16. Cancer, except skin basal cell carcinoma completely excised with no chemotherapy or radiation with a follow up that is negative. Volunteers with cancer in full remission for more than five years after diagnosis are acceptable
• •17. Current use of any prescribed or over-the counter medications and/or supplements that may affect body weight or metabolism, as assessed by the QI
• •18. Regular use of tobacco products within 6 months of baseline and during the study period, as assessed by the QI
• •19. Chronic inhalation and edible use of cannabinoid products (\>1 time/month). Occasional users must agree to wash out and abstain during the study period
• •20. Alcohol intake average of \>2 standard drinks per day
• •21. Alcohol or drug abuse within the last 12 months
• •22. Clinically significant abnormal laboratory results at screening, as assessed by the QI
• •23. Blood donation 30 days prior to baseline, during the study, or a planned donation within 30 days of the last study visit
• •24. Participation in other clinical research studies 30 days prior to baseline, as assessed by the QI
• •25. Individuals who are unable to give informed consent
• •26. Any other condition or lifestyle factor, that, in the opinion of the QI, may adversely affect the participant's ability to complete the study or its measures or pose significant risk to the participant