Early Versus Conventional Cessation of Hydrocortisone in Septic Shock

Inclusion Criteria

• •Patient \>= 18 years old
• •Diagnosis Septic shock from the definition of SEPSIS III criteria in intensive care unit or medicine ward or surgical ward at Siriraj hospital
• •Received at least 1 catecholamines and hydrocortisone at least 200 mg/d
• •Maintain mean arterial pressure \>= 65 mmHg even if titrate down catecholamines until low dose (\<=0.1 mcg/kg/min)