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Gastric Myoelectric Activity, Inflammatory, Dietary, and Body Composition Changes During Weight Loss Via Bariatric Surgery and Lifestyle Modification
Gastric myoelectric, inflammatory, and hormonal responses, body compositional, energy expenditure, and metabolic changes during the development of obesity and the weight loss process are underinvestigated. This project studied the myoelectrical inflammatory and hormonal responses of the stomach, in addition to energy expenditure and body composition changes during weight loss via bariatric surgery and lifestyle intervention.
Gastric myoelectric, inflammatory, and hormonal responses, body compositional, energy expenditure, and metabolic changes during the development of obesity and the weight loss process are underinvestigated. This project studied the myoelectrical, inflammatory, and hormonal responses of the stomach, in addition to energy expenditure and body composition changes during weight loss via bariatric surgery and lifestyle intervention. Methods: We recruited 79 participants who were assigned to three groups: bariatric surgery (BS group n=27), lifestyle intervention (LS group, n=22), and waitlist control (C group n=30). For all participants, electrogastrography, inflammatory cytokines, gastric hormones analysis, body composition analysis, energy expenditure, and dietary assessment were done at baseline and at 6 months.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
No
College of Applied Medical Sciences
Riyadh, Saudi Arabia
Start Date
June 1, 2021
Primary Completion Date
June 30, 2022
Completion Date
September 10, 2022
Last Updated
March 20, 2023
79
ACTUAL participants
Sleeve gastrectomy
PROCEDURE
Lifestyle intervention
DIETARY_SUPPLEMENT
Control
OTHER
Lead Sponsor
King Saud University
Collaborators
NCT07472881
NCT01143454
Data Source & Attribution
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