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UNKNOWNNANCT05739695

A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions

Peripheral pulmonary lesions are of growing importance in respiratory field. Early detection of lung cancer, tuberculosis and other diseases often needs a bronchoscopic investigation with different ty...

Lead sponsor: Ilya Sivokozov•6 locations•View source on ClinicalTrials.gov

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Contacts

Ilya Sivokozov, MD PhD

CONTACT

+79670457905 sivokozov@bronchology.ru

Sponsors

Lead Sponsor

Ilya Sivokozov

Current randomized clinical study is intended to compare three different modalities of navigation in bronchial tree - virtual bronchoscopy, radial EBUS and combination of both techniques. Around 300 patients with incidentally detected peripheral pulmonary lesions will be enrolled in 9 centers among Russia. All patients after obtaining an informed consent will be randomized in 1:1:1 fashion to three study groups depending on type of navigation technique used. All patients will undergone navigational bronchoscopy with rEBUS (group A), VBN (group B) and rEBUS+VBN (group C), data on diagnostic efficacy and safety of each modality of navigation will be analyzed.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Patients with newly diagnosed unverified solitary or multiple (up to 3) peripheral pulmonary lesions (PPLs)
•2. PPL size 5 - 40 mm
•3. Actual chest CT scan (\<31 days prior to navigation bronchoscopy), collimation 1 mm, pulmonary window, DICOM format
•4. Age \> 18 years
•5. Signed Informed consent form
•6. Willing and ability to undergone a navigational bronchoscopy

Exclusion Criteria

•1. Unability to undergone navigation bronchoscopy for any reason
•2. Any malignant disease during last 36 months
•3. Known central endobronchial lesion of any cause
•4. HIV-infection

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 6, 2024Terms

Trial snapshot

StatusUNKNOWN

PhaseNA

Enrollment300

Start dateFeb 2022

Last updatedFeb 6, 2024

Condition

Lung Cancer Tuberculosis Pneumonia

Locations shown

Chelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine

Chelyabinsk

Kurgan Regional Oncological Dispensary

Kurgan

Central TB Research Institute

Moscow

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 6, 2024Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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