Immunological Characteristics of Preclinical IBD

Inclusion Criteria

• •Male or female ≥18 years of age at baseline.
• •New diagnosis of IBD during a CRC screening colonoscopy, based on the criteria from the European Crohn's and Colitis Organization (33, 34).
• •Presence of a chronic inflammatory infiltrate and histological diagnosis compatible with IBD.
• •The patient must be asymptomatic at diagnosis and without previous symptoms suggestive of IBD.
• •Time interval between the index colonoscopy and the baseline visit up to 3 months.
• •Male or female ≥18 years of age at baseline.
• •Recent diagnosis of IBD, with \<3 months from symptoms onset.
• •Time interval between the index colonoscopy and the baseline visit up to 3 months.
• •Male or female ≥18 years of age at baseline.
• •No endoscopic signs of IBD after a complete ileo-colonoscopy within the CRC screening program.
• •Time interval between the index colonoscopy and the baseline visit up to 3 months.