Pharmacogenomics on Individualized Precise Treatment of Patients With Depression

Exclusion Criteria

• •1. Patients with schizophrenia, schizoaffective disorder, bipolar affective disorder, mental retardation, generalized developmental disorder, delirium, dementia, cognitive dysfunction, alcohol dependence and other diagnoses;
• •2. Suffering from serious organic diseases, such as diabetes, thyroid disease, hypertension, cardiovascular disease, brain injury, cerebral ischemia or hemorrhage;
• •3. Patients with narrow angle glaucoma;
• •4. History of epilepsy and febrile convulsion;
• •5. Those who have taken drugs in the past;
• •6. Syphilis specific antibody and AIDS antibody are positive;
• •7. Those who received MECT or rTMS and other neuromodulation therapy one month before enrollment;
• •8. The risk assessment indicates that there is a serious suicide attempt or excitement;
• •9. Laboratory examination indicates that liver function and renal function are impaired;
• •10. Pregnant or lactating women, or those who plan to have a pregnancy in the near future;
• •11. Other contraindications of antidepressants.