Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Vibeke Backer
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients ≥ 18 years old at the time of signed informed consent (no upper limit)
Patients who are referred to the outpatient clinic for the following reasons:
* Doctor's diagnosis of CRS
NPS ≥ 2+2 out of a score of 8 (max)
Severity measured as an SNOT22 score \> 35
One FESS surgery in general anaesthesia performed prior to inclusion (no time limitations)
No course of systemic steroids within the last 3 months, whereas a daily low dose is allowed
Possible doctor's diagnosis of asthma
Type 2 inflammation
You may not be if
Patients who, because of language barriers, are not able to understand written information and, thus, are not able to answer questionnaires
Patients who currently receive biologics for any other disease
Patients who have previously or currently received biologics for CRS or asthma
Patients who are not able to give informed consent (i.e., patients who are permanently incapable)
Patients who meet ≥1 of the following:
* Malignant lung disease
* Cardiac disease of clinical importance
* Current pregnancy and breastfeeding, as well as planning to be pregnant in the near future
* Unwillingness to have FESS performed
Patients needing FESS or systemic steroids (OCS) during the study period will be excluded after an unscheduled visit (last observation carried forward (LOCF))
