Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial）

Exclusion Criteria

• •1. Target lesion is not caused by atherosclerotic disease；
• •2. Target lesion is located at the opening of the common carotid artery；
• •3. Patient has severe lesion calcification that may restrict the full deployment of the carotid
• •4. Patient has a total occlusion of the target carotid arteries
• •5. Patient has a large number of acute or subacute thrombi and arteriovenous malformations near the target lesion
• •6. Patient has a severe stenosis or occlusion in series with target lesions
• •7. Patient has known severe carotid stenosis contralateral to the target lesion
• •8. Patient need angioplasty in other parts (including intracranial and extracranial) at the same time or within 30 days after procedure
• •9. Patient has a symptomatic severe stenosis of other blood vessels (including intracranial and extracranial) except carotid artery
• •10. Patient is experiencing (or has experienced) an evolving, acute, or recent disabling stroke or intracranial hemorrhage
• •11. Patient has a massive stroke or myocardial infarction
• •12. Patient has a intracranial aneurysm
• •13. Patient has a coagulation dysfunction or abnormal bleeding, or contraindications to heparin and antiplatelet drugs
• •14. Patient has known sensitivity to contrast agent
• •15. Patient has a platelet \< 90 × 109 / L, severe liver and kidney injury, and severe dysfunction of important organs such as heart, lung, liver and kidney
• •16. Patient has a uncontrollable severe hyperemia
• •17. Patient has a bradycardia
• •18. mRS≥3
• •19. Patient has life expectancy of less than one year
• •20. Patient is currently enrolled in another investigational study protocol
• •21. Females who are pregnant or in lactation
• •22. Other conditions not suitable for inclusion judged by the researcher -