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Ultrasound-guided Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia in Inguinal Hernia Repair Under General Anesthesia: a Randomized Controlled Study
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
Inguinal hernia repair is one of the most common surgical procedures in the world. Annually, more than 20 million inguinal hernia repairs are conducted worldwide. Uncontrolled postoperative pain increases the incidence of postoperative complications. Regional blocks, as a part of multimodal analgesia, can improve pain control in the postoperative period and reduce complications that may arise from using a single mode of analgesia. For example, reliance on opioid analgesia increases the incidence of pruritus, nausea, and vomiting, as well as respiratory depression. Hebbard first described the ultrasound (US)-guided transversalis fascia plane (TFP) block in 2009. A local anesthetic (LA) injected between the transversus abdominis muscle and its deep investing fascia will block the anterior and the lateral branches of the T12 and L1 nerves. Erector spinae plane block (ESPB) is a type of facial plane block in which local anesthetic is administered in the plane located between the erector spinae muscle and thoracic transverse process. ESPB blocks the transmission of nociceptive stimuli through the dorsal/ventral rami of the spinal nerve roots, prevents afferent stimuli transmission, and inhibits efferent activation of the sympathetic nervous system and can thus provide both somatic and visceral sensory blockade, which would make it an ideal regional anesthetic technique for abdominal surgery.The effect of ESPB is also achieved through the block of the lateral, posterior, and anterior thoracic wall resulting in multiple levels sensory blocks. Additional proposed mechanism of action could be explained by the epidural spread of the anesthetics.
Age
20 - 65 years
Sex
MALE
Healthy Volunteers
No
Assiut University
Asyut, Egypt
Start Date
December 1, 2022
Primary Completion Date
August 31, 2025
Completion Date
August 31, 2025
Last Updated
March 17, 2026
43
ACTUAL participants
Transversalis fascia plane (TFP) block
PROCEDURE
Erector Spinae Plane (ESP) Block
PROCEDURE
Lead Sponsor
Assiut University
NCT07482709
NCT07041736
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07310953